分子对接技术在药物设计学教学中的应用

Application of Molecular Docking Technology in Teaching Drug Design

摘要: 药物设计学是一门涉及新药研究开发程序、方法手段和要求的新兴学科,涵盖多门学科知识,在新药研发类综合型人才培养的知识体系中具有重要地位。本文采用模拟实操教学法,以人参皂苷抗阿尔茨海默病为例,将计算机辅助药物设计中的分子对接技术应用于实战演练,以提升理论教学的效果,加深学生对课堂理论知识的理解,提升学生的创新思维能力和实践运用能力。

Abstract: Drug design is an emerging discipline that involves the processes,methodologies,and requirements of new drug research and development,encompassing knowledge from multiple disciplines and holding a significant position in the education system for training comprehensive talent in new drug research and development.This paper adopts a simulated practical operation teaching method,taking the use of ginsenosides in the treatment of Alzheimer's disease as an example,to apply molecular docking techniques from computer-aided drug design in practical exercises.This enhances the effectiveness of theoretical teaching,deepens students' understanding of classroom theoretical knowledge,and improves students' innovative thinking and practical application skills.