Abstract: The experimental course in Natural Medicinal Chemistry is a crucial extension and support for the theoretical course,and it serves as an effective platform for cultivating students' innovative thinking and capabilities.However,most experimental teaching still follows traditional models,which limit the development of students' innovative abilities.This study introduces,for the first time,an integrated model of "Science-Education-Research-Innovation" into the Natural Medicinal Chemistry experiment course,with the core focus on scientific research,the prerequisite of solid theoretical foundations,the cultivation of research skills as the fundamental goal,and the enhancement of innovative potential as the target.This model offers a new pathway for improving the effectiveness of innovation training in Natural Medicinal Chemistry experiment teaching and achieving the goal of cultivating innovative talents.