Abstract: Analytical chemistry is an important subject foundation course for pharmacy majors, and it characterized with the integration of multidisciplinary knowledge and close connection with scientific research, production and life practices. This paper is guided by the student-centered Dee Fink framework for instructional design, and builds a hybrid model (online & offline) based on curriculum center platform of Shanghai University of Traditional Chinese Medicine. The platform is applied to all aspects of the learning and assessment of analytical chemistry in major of pharmacy. This study aims to explore a blended teaching model that stimulates students' interest in learning and enhances their independent learning capacity and innovation competence.