Abstract: Chemistry of Chinese Materia Medica is an interdisciplinary course that places a high demand on students' practical skills and capacity for innovation.To enhance the quality and effectiveness of course instruction,this study explores a research-integrated teaching model supported by a case library derived from original research,aiming to stimulate and develop students' innovative thinking and practical abilities.The teaching team selected 23 representative research cases from their academic outputs,aligning them with the course syllabus and employing pedagogical methods such as knowledge transfer,comparative analysis,and interactive teaching.Students were guided to comprehend fundamental concepts,principles,and methodologies of traditional Chinese medicinal chemistry through in-depth engagement with real research cases.Evaluations based on classroom performance,assignments,surveys,and participation in research competitions indicate that this model broadens students' intellectual horizons,fosters scientific interest,promotes active learning,and enhances their research literacy and analytical thinking.