Abstract: In traditional verification experiments, how to stimulate students’ enthusiasm for learning and guide them to actively think about the problems in organic chemistry laboratory teaching is a pressing issue.Taking the “chromatography” experiment as an example, the teaching team adopts various methods, including creating teaching scenarios, introducing digital teaching tools, and writing personalized lab reports, to enhance students’ interest in learning and improve teaching effectiveness.This approach enables students to thoroughly understand the principles and applications of chromatography, while enhancing their inquiry and critical thinking skills.