Abstract: “Triple medical coordination and governance” is a key component of deepening healthcare system reforms and an important initiative for safeguarding public health and well-being.Pharmacoeconomics is widely applied in the contexts of medical insurance, healthcare, and pharmaceuticals, and serves as an important theoretical support and methodological foundation for the development of “triple medical coordination and governance”.Integrating ideological and political education into the teaching and training system of Pharmacoeconomics courses is an important direction to cultivate pharmaceutical professionals with innovative awareness and social responsibility, in response to the demands of the times.This study proposes several ideological and political education teaching reform pathways for Pharmacoeconomics, including classroom group debates, simulated negotiation interactive teaching, integration of theoretical learning with practical internships, flipped classroom role-playing, and “Triple Medical” expert lectures.These approaches aim to stimulate students’ intrinsic motivation for learning and guide them to develop a career pursuit and value orientation focused on contributing to the healthcare sector.