Abstract: With Chinese pharmaceutical companies gradually transitioning from the traditional field of generic drugs to the field of innovative drugs, the demand for pharmaceutical research and innovation talents with scientific literacy is increasing.The formation of scientific research thinking is an important foundation for cultivating research abilities.By introducing ideological and political elements into experimental teaching, adopting various teaching models and methods such as Problem-Based Learning(PBL),flipped classrooms, design-like experiments, and synchronous learning using different approaches, multiple exploratory research scenarios are created to stimulate students' curiosity, arouse their interest in learning, guide them to observe experimental phenomena, and cultivate students' scientific research literacy such as comprehensive analysis and problem-solving.