Abstract: With the introduction of the newly revised Vocational Education Law of the People's Republic of China and the Measures for the Management of Textbooks in Vocational Colleges,the country has put forward new requirements for the development of textbooks in vocational colleges.Shanghai Pharmaceutical School has explored and summarized an effective management mechanism for the development of textbooks in vocational colleges through practice,aiming to establish a refined management and control system for the full process of textbook development in vocational colleges,providing reference for related institutions.