Abstract: Comprehensive promotion of ideological and political construction into university curriculum development is the strategic measure to implement the fundamental task of building morality and cultivating students in higher education institutions.Pharmacology is an important professional course in medical education, which contains rich ideological and political elements.Based on the issue of hypertension medication safety under the background of "anti-epidemic",this article focuses on a pedagogical case of "pharmacological effect of renin angiotensin system (RAS)".The paper discusses how to make use of the problem chain teaching design method of "connection of three principles",deeply excavates the ideological and political elements in the course,and explores the opportunities and challenges confronted by the ideological and political-embedded teaching philosophy of pharmacology.