Abstract: In recent years,China's biopharmaceutical industry has flourished with substantial support from various government policies.Biochemistry and Molecular Biology,as essential foundational courses for biopharmaceutical-related disciplines,are closely linked with all aspects of the biopharmaceutical industry.This paper,grounded in the Outcome-Based Education (OBE) philosophy,explores the reform and innovation of teaching models in Biochemistry and Molecular Biology with the aim of cultivating innovative talents aligned with the biopharmaceutical industry,and addressing the current shortage of innovative professionals and the weakness in foundational research within the industry.