Abstract: To enhance the effectiveness of integrating ideological and political elements into the pharmacological toxicology curriculum,this study explores the instructional pathways and strategies for embedding such content based on Problem-Based Learning (PBL) methodology.The objective is to achieve a synergistic resonance between knowledge transmission and values-based guidance.This approach contributes to the goal of moral education and offers insights for developing a pharmacy talent training system characte-rized by medical proficiency,pharmaceutical expertise,and strong research capabilities.