Abstract: In response to issues in the teaching of Analytical Chemistry and Pharmaceutical Analysis,such as students' low enthusiasm for theoretical and laboratory courses,fragmented understanding of theoretical knowledge,insufficient experimental skills,and limited capacity for independent inquiry and problem-solving,this study innovatively integrates Problem-Based Learning (PBL) with team-based teaching methods.The results indicate that the PBL team-based teaching approach not only stimulates students' learning motivation but also enables them to systematically,comprehensively,and internally integrate theoretical knowledge and experimental skills related to Analytical Chemistry and Pharmaceutical Analysis during problem-solving processes.Additionally,it enhances students' ability to independently address issues related to drug quality analysis and research and development,significantly improving teaching quality and fostering scientific research competence.