Abstract: With the continuous advancement of the Healthy China initiative, cultivating high-quality pharmaceutical talents has become a central concern in pharmacy education.In response to existing issues in undergraduate pharmacy programs, Shenyang Pharmaceutical University has established and implemented a first-class undergraduate pharmacy education framework guided by the principles of “conceptual leadership, pathway exploration, and mechanism innovation”.The model is structured around “one core, two priorities, three levers, and four safeguards”,aiming to comprehensively strengthen the connotation of undergraduate pharmacy education and enhance the overall quality of talent cultivation.