Abstract: Organic Spectroscopic Analysis is an applied course for the structural identification and analysis of organic compounds by means of spectroscopy. Through the pedagogical method of "skill leading, fun learning and innovation" under the PDA model, an attempt is carried out to change the current situation of insufficient training on curriculum cultivation, students' weariness of learning and the challenges teachers come across during instruction. This course emphasizes the cultivation of students' capability and overall quality development. Through the purposeful stepwise in-depth curriculum design, students learn and play simultaneously, and imperceptibly improve their team cooperation spirit, learning competence and innovation ability. The course content guides students to expand ways of thinking, solve practical problems, and ultimately achieve the educational objectives of the improvement of students' cognition skills, cooperation spirit, innovation competence and vocational capacity.