Abstract: Addressing the disconnection between theory and practice in the curriculum of professional master's programs in pharmacy,this study proposes a case-based teaching reform strategy driven by both the innovation chain and the industrial chain in the pharmaceutical field—referred to as the "double-chain driven" model.Thirteen industry-contextualized teaching cases were developed,covering three core courses and seven elective courses and two elective courses,thereby constructing a full-chain case system spanning pharmaceutical R&D,manufacturing,and clinical application.Through the use of hybrid teaching formats—including online and offline integration,Problem-Based Learning (PBL),and flipped classrooms—students are guided to apply their professional knowledge in solving real-world problems through case analysis and discussion.This approach effectively enhances the integration of theoretical learning and practical application,offering a valuable model for cultivating high-level,application-oriented pharmacy professionals capable of engaging in innovative pharmaceutical practice.