Abstract: The rapid development of new-generation chatbots,represented by GPT-4o,and educational models such as ChatGPT-Edu,presents new opportunities for the deep integration of artificial intelligence (AI) and higher education,as well as for the digital transformation of curriculum ideological and political education.Introduction to Pharmacy is a cornerstone course for instilling moral education in pharmacy undergraduates and serves as a guiding course for first-year students embarking on their pharmacy studies.Using Introduction to Pharmacy as a pilot,this paper explores the construction strategies for AI-driven curriculum ideological and political education and examines how AI-based education reshapes the foundational logic of curriculum ideological and political education.The study aims to provide a practical pathway for applying AI-empowered innovations in curriculum ideological and political education within higher education.