Abstract: The content of pharmacology teaching is complex and difficult, and the students are not very interested in learning.In order to improve students' enthusiasm for learning and self-learning awareness, the teaching mode of knowledge teaching assisted by literature discussion was introduced into pharmacology teaching, which can improve students' interest in pharmacology courses, deepen their understanding and memory of professional knowledge, and cultivate students' English literature reading ability, logical thinking ability, generalization ability and language expression ability at the same time.