Abstract: Ideological and political education with professional knowledge as the carrier is an important approach to realize the "Three Comprehensive Education" in universities.Pharmaceutical frontier is a demonstration course in ideological and political education for graduate students at Shanghai Jiao Tong University.Taking the exploration and practice of curriculum ideological and political education in the course teaching as an example,this article discusses the integration of knowledge transmission,competence cultivation,and value shaping under the guidance of the course objectives of the "three trinity" curriculum.It combines the goals of professional talent cultivation and the characteristics of the curriculum,explores and organizes ideological and political elements,clarifies the points of integration,teaching methods,and carrier paths,develops teaching resources for curriculum ideological and political education,and establishes a curriculum system with ideological and political core philosophy.