Abstract: In view of the characteristics of pharmaceutics as a core discipline, the concept of STEM education has been incorporated into course design to foster students’ autonomy, lifelong learning ability, and advanced thinking skills.Centered on the main thread of pharmaceutical preparations and dosage forms, the instructor optimized the pharmaceutics curriculum system, initiating reform from formulation design and integrating the STEM 9E instructional model.A comprehensive process-oriented and multi-task learning and assessment system was established across pre-class, in-class, and post-class stages.This approach encourages students to propose high-quality, in-depth questions, transcend the spatial and temporal limitations of learning, and effectively enhance their advanced cognitive abilities.The reform contributes to improving the overall quality of pharmaceutical talent cultivation and aligns educational outcomes with the evolving demands of the pharmaceutical industry.